Source of Support: None, Conflict of Interest: None
Only few studies on zinc status in hypogonadotropic hypogonadism patients are available from India; however no study has been reported on the therapeutic effect of zinc supplementation on these patients. The present study was undertaken to assess the zinc status and hormonal profile in patients presenting with isolated hypogonadotropic hypogonadism and then to assess the therapeutic effect of zinc supplementation in those patients found to be zinc deficient. Zinc supplementation study on hypogonadism patients showed good improvement in terms of erythrocyte and hair zinc levels and also showed improvement in testosterone levels in a proportion of patients. When clinically evaluated. 67% of the patients have shown improvement suggesting that zinc therapy can be effectively used to treat a subset of patients with hypogonadotropic hypogonadism.