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CASE REPORT
Year : 2011  |  Volume : 15  |  Issue : 3  |  Page : 220-223

Primary adrenal lymphoma: Differential involvement with varying adrenal function


1 Department of Medical Oncology, Sher-I-Kashmir Institute of Medical Sciences, Srinagar, Kashmir, India
2 Department of Endocrinology, Sher-I-Kashmir Institute of Medical Sciences, Srinagar, Kashmir, India
3 Department of Pathology, Sher-I-Kashmir Institute of Medical Sciences, Srinagar, Kashmir, India

Correspondence Address:
Bashir Ahmad Laway
Department of Endocrinology, Sher-I-Kashmir Institute of Medical Sciences, Srinagar, Kashmir
India
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/2230-8210.83414

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Primary adrenal Non-Hodgkin's lymphoma is rare. The symptoms of the disease and response to treatment are variable depending on the type of lymphoma, tumor size, and presence of adrenal insufficiency. We report two cases of primary adrenal lymphoma who had varied presentations. One presenting with abdominal pain and weight loss was documented to have unilateral disease without any adrenal insufficiency and showed a good response to combination chemotherapy, while the second one had bilateral adrenal involvement with adrenal insufficiency and died after second chemotherapy. Functional adrenal involvement in lymphoma depends on the extent of involvement; patients with bilateral involvement almost always have adrenal insufficiency.


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