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Year : 2012  |  Volume : 16  |  Issue : 2  |  Page : 164-176

Rickets-vitamin D deficiency and dependency


1 Department of Nephrology, Osmania Medical College and General Hospital, Hyderabad, Andhra Pradesh, India
2 Department of Endocrinology, Osmania Medical College and General Hospital, Hyderabad, Andhra Pradesh, India

Correspondence Address:
Manisha Sahay
My Nest, 6-3-852/A, Ameerpet, Hyderabad - 500 016, Andhra Pradesh
India
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/2230-8210.93732

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Rickets is an important problem even in countries with adequate sun exposure. The causes of rickets/osteomalacia are varied and include nutritional deficiency, especially poor dietary intake of vitamin D and calcium. Non-nutritional causes include hypophosphatemic rickets primarily due to renal phosphate losses and rickets due to renal tubular acidosis. In addition, some varieties are due to inherited defects in vitamin D metabolism and are called vitamin D dependent rickets. This chapter highlights rickets/osteomalacia related to vitamin D deficiency or to inherited defects in vitamin D metabolism. Hypophosphatemic rickets and rickets due to renal tubular acidosis are discussed in other sections of the journal.


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