Home | About us | Editorial board | Search | Ahead of print | Current issue | Archives | Submit article | Instructions | Subscribe | Contacts | Advertise | Login 
 
Search Article 
  
Advanced search 
  Users Online: 1967 Home Print this page Email this page Small font sizeDefault font sizeIncrease font size  
ORIGINAL ARTICLE
Year : 2012  |  Volume : 16  |  Issue : 3  |  Page : 414-416

Pulmonary function tests in patients with primary hyperparathyroidism


1 Department of Endocrinology, Postgraduate Institute of Medical Education and Research, Chandigarh (UT), India
2 Department of Pulmonary Medicine, Postgraduate Institute of Medical Education and Research, Chandigarh (UT), India
3 Department of Surgery, Postgraduate Institute of Medical Education and Research, Chandigarh (UT), India
4 Department of Gastroenterology, Postgraduate Institute of Medical Education and Research, Chandigarh (UT), India
5 Department of Pathology, Postgraduate Institute of Medical Education and Research, Chandigarh (UT), India

Correspondence Address:
Sanjay Kumar Bhadada
Department of Endocrinology, Postgraduate Institute of Medical Education and Research, Chandigarh (UT)
India
Login to access the Email id

Source of Support: None, Conflict of Interest: None


DOI: 10.4103/2230-8210.95685

Rights and Permissions

Context: There is limited information on respiratory muscle functions in patients with primary hyperparathyroidism (PHPT). AIM: To assess respiratory muscle dysfunction in patients with PHPT. Setting and Design: This prospective study was carried between January 2005 and December 2006 by the Department of Endocrinology at the Postgraduate Institute of Medical Education and Research, Chandigarh. Materials and Methods: PHPT was defined as elevated parathyroid hormone in the presence of hypercalcemia. Spirometry was performed using a dry rolling seal spirometer and spirometric indices like forced vital capacity (FVC), forced expiratory volume in first second (FEV 1 ), and FEV 1 /FVC ratio were measured using standard guidelines. Results: Thirty patients were studied with a mean age of 37.1 ± 2.4 years and 18 were women. The most common presenting symptoms were fatigue (75.0%) and bone pain (60.70%). The mean (±SD) of percentage predicted FVE 1 , FVC, FEV 1 /FVC ratio, PEF, and FEF were 98.7 ± 16.1, 93.9 ± 14.7, 84.5 ± 3.4, 89.3 ± 22.5, and 99.7 ± 33.6, respectively. Two had obstructive lung disease and two had restrictive lung disease. We did not find correlation with preoperative serum calcium, phosphate, and PTH with FVE 1 , FVC, FEV 1 /FVC ratio, PEF, and FEF. Conclusion: Elevated calcium, low phosphate, and elevated PTH levels in patients with moderate to severe PHPT do not significantly affect respiratory muscle functions.


[FULL TEXT] [PDF]*
Print this article     Email this article
 Next article
 Previous article
 Table of Contents

 Similar in PUBMED
   Search Pubmed for
   Search in Google Scholar for
 Related articles
 Citation Manager
 Access Statistics
 Reader Comments
 Email Alert *
 Add to My List *
 * Requires registration (Free)
 

 Article Access Statistics
    Viewed1313    
    Printed52    
    Emailed0    
    PDF Downloaded281    
    Comments [Add]    

Recommend this journal