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Year : 2012  |  Volume : 16  |  Issue : 5  |  Page : 728-739

Low renin hypertension


Deparment of Nephrology, Osmania General Hospital, Hyderabad, Andhra Pradesh, India

Correspondence Address:
Manisha Sahay
Deparment of Nephrology, Osmania Medical College and General Hospital, 6-3-852/A, Ameerpet, Hyderabad - 16, Andhra Pradesh
India
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/2230-8210.100665

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Low renin hypertension is an important and often underdiagnosed cause of hypertension. It may be associated with high aldosterone levels as in Conn's syndrome or low aldosterone levels as in Liddle syndrome, and syndrome of apparent mineralocorticoid excess, glucocorticoid remediable hypertension etc. Some forms of essential hypertension are also associated with low renin levels. Hypokalemia may be an important finding in low renin hypertension. The aldosterone to renin ratio helps in correct diagnosis. The treatment varies with etiology hence an accurate diagnosis is essential. Aldosterone antagonists play an important role in medical management of some varieties of low renin hypertension.


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