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Year : 2012  |  Volume : 16  |  Issue : 6  |  Page : 894-898

Hypoglycemia in type 2 diabetes: Standpoint of an experts' committee (India hypoglycemia study group)

1 Department of Diabetology, Dr. Mohan's Diabetes Specialties Centre and Madras Diabetes Research Foundation, WHO Collaborating Centre for Non Communicable Diseases Prevention and Control, Gopalapuram, Chennai, India
2 Department of Endocrinology, Lilawati Hospital, Bhatia Hospital and Grant Medical College, Mumbai, India
3 Department of Endocrinology, Postgraduate Institute of Medical Education and Research, Chandigarh, India
4 Manipal Hospital, Bangalore, India
5 Institute of Post Graduate Medical Education and Research and SSKM Hospital, Kolkata, India
6 Belgaum Diabetes Centre, Belgaum, India
7 Institute for Treatment and Research in Diabetes and Endocrinology, Pune, India
8 Madurai Institute of Diabetes and Endocrinology, Madurai, India
9 Sir Ganga Ram Hospital, New Delhi, India
10 Amrita Institute of Medical Sciences, Cochin, India
11 PRS Hospital, Trivandrum, India
12 MSD Pharmaceuticals Private Limited, New Delhi, India
13 Nigam Diabetes Centre, Jaipur, India
14 Gauhati Medical College, Guwahati, India
15 Care Hospitals, Hyderabad, India
16 Mysore Medical College, Mysore, India
17 Samatvam Diabetes Center, Bangalore, India
18 Banaras Hindu University, Varanasi, India
19 MV Hospital for Diabetes, Chennai, India
20 Indraprastha Apollo Hospital, New Delhi, India

Correspondence Address:
Vikram Singh
MSD Pharmaceuticals Private Limited, 6th Floor, Vatika Tower B, Sector 54, Gurgaon, Haryana 122 002
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Source of Support: The meeting of expert members of India hyypoglycemia study group was arranged for and funded by MSD Pharmaceuticals Pvt. Ltd, India, Conflict of Interest: Two members of India Hypoglycemia Study Group, Narang Prashant and Singh Vikram, are employees of MSD Pharmaceuticals Pvt. Ltd, India. The authors and other members of India Hypoglycemia Study Group acknowledged above, have received honoraria from MSD Pharmaceuticals Pvt. Ltd., towards the services provided.

DOI: 10.4103/2230-8210.102986

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The epidemic of type 2 diabetes and the recognition that achieving specific glycemic goals can substantially reduce morbidity have made the effective treatment of hyperglycemia a top priority. Despite compelling evidence that tight glycemic control is crucial for delaying disease progression, increased risk of hypoglycemia associated with such control underscore the complexity of diabetes management. In most cases, hypoglycemia results from an excess of insulin, either absolute or relative to the available glucose substrate and the factors perhaps exacerbating the risk are pharmacokinetic imperfections, behavioral, co-morbidities etc. Additionally, many patients remain undiagnosed, and many diagnosed patients are not treated appropriately. In this article, the challenges of hypoglycemia, confronting health care providers and their patients with diabetes, are discussed for making treatment decisions that will help minimize risk of hypoglycemia and eventually overcome formidable barriers to optimal diabetes management. Strategies to treat and minimize the frequency and severity of hypoglycemia without compromising on glycemic goals are also presented.

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