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CASE REPORT
Year : 2013  |  Volume : 17  |  Issue : 1  |  Page : 170-173

Oral manifestations of McCune-Albright syndrome


Department of Oral Medicine and Radiology, Career Post Graduate Institute of Dental Sciences and Hospital, Sitapur Road, Lucknow, Uttar Pradesh, India

Correspondence Address:
Konidena Aravinda
Department of Oral Medicine and Radiology, Career Post Graduate Institute of Dental Sciences and Hospital, Sitapur Road, Lucknow - 226 020, Uttar Pradesh
India
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DOI: 10.4103/2230-8210.107878

PMID: 23776876

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McCune- Albright Syndrome (MAS) is a rare fibrosseous lesion, characterized by a classic triad of polyostotic fibrous dysplasia (PFD), cafι -au-lait macules (CALM) and underlying endocrinopathies. We present the oral findings of an interesting case of MAS with relevant review of literature. A 30-year-old male presented to us with swelling of both jaws over a period of two years. Cutaneous examination revealed cafι - au - lait macule over the back, crossing the midline. Skeletal survey showed expansile, osteolytic, mixed radiolucent- radiopaque lesions in skull and jaw bones. Serum alkaline phosphatase was elevated (388 IU/L), with normal calcium, phosphorus, parathyroid hormone and 25 hydroxy vitamin D levels. Diagnosis of McCune- Albright syndrome was made and he was treated with parenteral bisphosphonates (intravenous Zoledronate 4 mg) and is under follow up for surgical recontouring of the jaws. Early recognition facilitates better treatment and improves prognosis by reducing the morbidity.


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