Home | About us | Editorial board | Search | Ahead of print | Current issue | Archives | Submit article | Instructions | Subscribe | Contacts | Advertise | Login 
 
Search Article 
  
Advanced search 
  Users Online: 1025 Home Print this page Email this page Small font sizeDefault font sizeIncrease font size  
REVIEW
Year : 2013  |  Volume : 17  |  Issue : 1  |  Page : 50-59

Endocrinology of parturition


1 Department of Endocrinology, Medwin hospital, Hyderabad, Andhra Pradesh, India
2 Department of Obstetrics and Gynecology, Riyadh Care Hospital, Riyadh, Saudi Arabia
3 Department of Pharmaceutics, Roland Institute of Pharmaceutical Sciences, Orissa, India
4 Department of Anesthesia, Central Security hospital, Riyadh, Saudi Arabia
5 Department of Medicine, MKCG Medical College, Berhampur, Orissa, India

Correspondence Address:
Sunil K Kota
Department of Endocrinology, Medwin Hospitals, Chiragh Ali Lane, Nampally, Hyderabad 500 001, Andhra Pradesh
India
Login to access the Email id

Source of Support: None, Conflict of Interest: None


DOI: 10.4103/2230-8210.107841

Rights and Permissions

The myometrium must remain relatively quiescent during pregnancy to accommodate growth and development of the feto-placental unit, and then must transform into a highly coordinated, strongly contracting organ at the time of labour for successful expulsion of the new born. The control of timing of labour is complex involving interactions between mother, fetus and the placenta. The timely onset of labour and delivery is an important determinant of perinatal outcome. Both preterm birth (delivery before 37 week of gestation) and post term pregnancy (pregnancy continuing beyond 42 weeks) are both associated with a significant increase in perinatal morbidity and mortality. There are multiple paracrine/autocrine events, fetal hormonal changes and overlapping maternal/fetal control mechanisms for the triggering of parturition in women. Our current article reviews the mechanisms for uterine distension and reduced contractions during pregnancy and the parturition cascade responsible for the timely and spontaneous onset of labour at term. It also discusses the mechanisms of preterm labour and post term pregnancy and the clinical implications thereof.


[FULL TEXT] [PDF]*
Print this article     Email this article
 Next article
 Previous article
 Table of Contents

 Similar in PUBMED
   Search Pubmed for
   Search in Google Scholar for
 Related articles
 Citation Manager
 Access Statistics
 Reader Comments
 Email Alert *
 Add to My List *
 * Requires registration (Free)
 

 Article Access Statistics
    Viewed10366    
    Printed60    
    Emailed3    
    PDF Downloaded1603    
    Comments [Add]    
    Cited by others 26    

Recommend this journal