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REVIEW ARTICLE
Year : 2013  |  Volume : 17  |  Issue : 3  |  Page : 422-429

A fish a day, keeps the cardiologist away! - A review of the effect of omega-3 fatty acids in the cardiovascular system


1 Department of Medicine, Christian Medical College, Ludhiana, Punjab, India
2 Department of Cardiology, Christian Medical College, Ludhiana, Punjab, India

Correspondence Address:
Jubbin J Jacob
Department of Medicine, Endocrine and Diabetes Unit, Christian Medical College, Ludhiana, Punjab - 141 008
India
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/2230-8210.111630

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Dyslipidemia and its consequences are emerging as epidemics with deleterious consequences on cardiovascular (CV) health. The beneficial effects of omega-3-fatty acids on cardiac and extra cardiac organs have been extensively studied in the last two decades, and continue to show great promise in the primary and secondary prevention of cardiovascular diseases (CVDs). Omega-3-fatty acid supplementation has been proven to have beneficial action on lipid profile, cytokine cascade, oxidant-anti-oxidant balance, parasympathetic and sympathetic tone and nitric oxide synthesis. This review summarizes the current knowledge on the basis of its cardiac and non-cardiac benefits, present results from clinical trials and the recommendations for its use in cardiac diseases and dyslipidemias.


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