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CASE REPORT
Year : 2013  |  Volume : 17  |  Issue : 3  |  Page : 529-531

Persistence of histoplasma in adrenals 7 years after antifungal therapy


1 Endocrinology Unit, Dr. RML Hospital, Delhi, India
2 Department of Pathology, Dr. RML Hospital, Delhi, India

Correspondence Address:
Bindu Kulshreshtha
Endocrinology Unit, Dr. Ram Manohar Lohia Hospital, Delhi
India
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/2230-8210.111679

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Adrenal histoplasmosis is an uncommon cause for adrenal insufficiency. The duration of treatment for adrenal histoplasmosis is not clear. Existing treatment regimens advocate antifungals given for periods ranging from 6 months to 2 years. We report here a rare case who showed persistence of histoplasma in adrenal biopsy 7 years after being initially treated with itraconazole for 9 months. This calls for a prolonged therapy with regular review of adrenal morphology and histology in these patients.


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