Home | About us | Editorial board | Search | Ahead of print | Current issue | Archives | Submit article | Instructions | Subscribe | Contacts | Advertise | Login 
 
Search Article 
  
Advanced search 
  Users Online: 257 Home Print this page Email this page Small font sizeDefault font sizeIncrease font size  
ORIGINAL ARTICLE
Year : 2018  |  Volume : 22  |  Issue : 3  |  Page : 379-386

The incidence of hypoglycemia among insulin-treated patients with Type 1 or Type 2 diabetes: Bangladeshi cohort of international operations-hypoglycemia assessment tool study


1 Department of Medicine and Endocrinology, BIRDEM General Hospital, Chittagong, Bangladesh
2 Department of Endocrinology, Bangabandhu Sheikh Mujib Medical University, Chittagong, Bangladesh
3 Department of Medicine, Bangladesh University of Health Sciences, Dhaka, Bangladesh
4 Department of Endocrinology, Chittagong Medical College Hospital, Chittagong, Bangladesh
5 Department of Endocrinology, Mymensingh Medical College and Hospital, Mymensingh, Bangladesh
6 Department of Endocrinology, Square Hospital, Dhaka, Bangladesh
7 Department of Endocrinology, Popular Medical College Hospital, Dhaka, Bangladesh
8 Department of Endocrinology, Dhaka Medical College and Hospital, Dhaka, Bangladesh
9 Department of Endocrinology, BIRDEM General Hospital, Dhaka, Bangladesh
10 Department of Clinical, Medical, Regulatory & Quality, Novo Nordisk Pharma (Private) Limited, Dhaka, Bangladesh

Correspondence Address:
Md. Faruque Pathan
Department of Medicine and Endocrinology, BIRDEM General Hospital, East Shawrapara, Mirpur, Dhaka 1216
Bangladesh
Login to access the Email id

Source of Support: None, Conflict of Interest: None


DOI: 10.4103/ijem.IJEM_545_17

Rights and Permissions

Objectives: The objective of this study was to assess the incidence of hypoglycemia in patients with type 1 diabetes mellitus (T1DM) or type 2 diabetes mellitus (T2DM) in Bangladeshi cohort of the International Operations-Hypoglycemia Assessment Tool study. Materials and Methods: Patients diagnosed with either T1DM or T2DM, aged ≥18 years, treated with insulin (any regimen) for >12 months, and completed self-assessment questionnaires (SAQs) to record demography, treatment information, and hypoglycemia during the 6-month retrospective and 4-week prospective periods (a total of 7 months) were enrolled in the study. Results: A total of 1179 patients were enrolled and completed the SAQ1 (T1DM, n = 25; T2DM, n = 1154). Almost all patients (T1DM: 100.0% [95% confidence interval (CI): 86.3%, 100.0%] and T2DM: 97.0% [95% CI: 95.9%, 97.9%]) experienced at least 1 hypoglycemic event prospectively. The estimated rates of any and severe hypoglycemia were 26.6 (95% CI: 19.8, 35.0) and 14.1 (95% CI: 9.3, 20.4) events per patient-per year (PPY), respectively, for patients with T1DM and 18.3 (95% CI: 17.4, 19.2) and 12.1 (95% CI: 11.4, 12.9) events PPY, respectively, for patients with T2DM during the prospective period. At baseline, mean glycated hemoglobin (HbA1c) (±standard deviation) was 8.1 (±1.8%) for T1DM and 8.8 (±1.8%) for T2DM. Hypoglycemic rate was independent of HbA1c levels and types of insulin. Conclusions: This is the first patient dataset of self-reported hypoglycemia in Bangladesh; results confirm that hypoglycemia is underreported.


[FULL TEXT] [PDF]*
Print this article     Email this article
 Next article
 Previous article
 Table of Contents

 Similar in PUBMED
   Search Pubmed for
   Search in Google Scholar for
 Related articles
 Citation Manager
 Access Statistics
 Reader Comments
 Email Alert *
 Add to My List *
 * Requires registration (Free)
 

 Article Access Statistics
    Viewed444    
    Printed1    
    Emailed0    
    PDF Downloaded95    
    Comments [Add]    

Recommend this journal