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ORIGINAL ARTICLE
Year : 2019  |  Volume : 23  |  Issue : 5  |  Page : 525-528

The impact of GE Lunar vs ICMR database in diagnosis of osteoporosis among South Indian subjects


Department of Endocrinology, Sri Ramachandra Medical College and Research Institute, Chennai, India

Correspondence Address:
Shriraam Mahadevan
Department of Endocrinology, Sri Ramachandra Medical College and Research Institute, Chennai
India
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/ijem.IJEM_142_19

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Objective: To study the effect of choosing ICMR reference values on the classification of bone mineral density in Indian patients. Design: Retrospective analysis of Dual Energy X-ray absorptiometry (DEXA) and clinical data. Patients: Totally, 316 patients aged more than 65 years attending a tertiary care hospital in South India who underwent DEXA scan were included in the study. Measurements: DEXA scan at femoral neck and lumbar spine. Results: A total of 316 patients were studied. The mean age was 61.98 ± 7.66 years. There were 46.84% females and 53.16% males. The average BMI was 26.37 ± 4.51. Of these patients, 46 had history of hip fracture (14.55%). The adoption of the ICMR normative data resulted in a significant increase in T scores in both the hip (+0.51, P < 0.05) and the spine (+1.64, P < 0.01). The adoption of ICMR normative values, resulted in reduction of osteoporosis prevalence from 26.58% to 5.06%. Conclusions: There is a clinically significant reduction in diagnosis of osteoporosis with the adoption of ICMR reference standard. Clinicians should be recommended to use raw BMD values in gm/cm2 in FRAX calculation and avoid the use of T scores, to avoid overestimation of fracture risk. If our results are replicated, the implications are enormous – Osteoporosis is currently being over diagnosed.


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