Indian Journal of Endocrinology and Metabolism

CASE-BASED REVIEW OF LITERATURE
Year
: 2012  |  Volume : 16  |  Issue : 3  |  Page : 436--440

Dysgerminoma in a female with turner syndrome and Y chromosome material: A case-based review of literature


Sunil Kumar Kota1, Kotni Gayatri2, Jaya Prakash Pani3, Siva Krishna Kota4, Lalit Kumar Meher5, Kirtikumar D Modi1 
1 Department of Endocrinology, Medwin Hospital, Hyderabad, Andhra Pradesh, India
2 Department of Obstetrics and Gynecology, Riyadh Care Hospital, Saudi Arabia
3 Department of Obstetrics and Gynecology, Apollo Hospitals, Bhubaneswar, Orissa, India
4 Department of Anesthesia, Central Security hospital, Riyadh, Saudi Arabia
5 Department of Medicine, MKCG Medical College, Berhampur, Orissa, India

Correspondence Address:
Sunil Kumar Kota
Department of Endocrinology, Medwin Hospitals, Chiragh Ali Lane, Nampally, Hyderabad-500001, Andhra Pradesh
India

We report a 17-year-old girl evaluated for primary amenorrhea. Cytogenetic analysis of the peripheral blood lymphocytes revealed normal autosomes with 46X inv (Y) confirming the diagnosis of Turner«SQ»s syndrome with Y cell line. Treatment was initiated with conjugated estrogen while recommending bilateral prophylactic oophorectomy to the patient. One year later the patient presented with abdominal mass, biopsy of the specimen following resection confirmed dysgerminoma originating from right ovary with no invasion or metastasis. The literature is reviewed with regard to the various pathogenetic mechanisms proposed for the development of germ cell tumors in ovary, the cytogenetic findings and recommendations to handle such scenario.


How to cite this article:
Kota SK, Gayatri K, Pani JP, Kota SK, Meher LK, Modi KD. Dysgerminoma in a female with turner syndrome and Y chromosome material: A case-based review of literature.Indian J Endocr Metab 2012;16:436-440


How to cite this URL:
Kota SK, Gayatri K, Pani JP, Kota SK, Meher LK, Modi KD. Dysgerminoma in a female with turner syndrome and Y chromosome material: A case-based review of literature. Indian J Endocr Metab [serial online] 2012 [cited 2020 Aug 9 ];16:436-440
Available from: http://www.ijem.in/article.asp?issn=2230-8210;year=2012;volume=16;issue=3;spage=436;epage=440;aulast=Kota;type=0