Indian Journal of Endocrinology and Metabolism

REVIEW ARTICLE
Year
: 2014  |  Volume : 18  |  Issue : 3  |  Page : 288--294

Endocrine dysfunction among adult patients with tuberculosis: An African experience


Davis Kibirige 
 Department of Medicine, Uganda Martyrs Hospital Lubaga, Kampala, Uganda

Correspondence Address:
Davis Kibirige
Department of Medicine, Uganda Martyrs Hospital Lubaga, Kampala-14130
Uganda

A broad spectrum of endocrine conditions has been reported among adult patients with tuberculosis in Africa. This review aims to describe the magnitude and pathogenesis of the following endocrinopathies among patients with tuberculosis in Africa: adrenal insufficiency, diabetes mellitus, disorders of calcium and vitamin D metabolism, thyroid dysfunction and hypogonadism. PubMed database and Google scholar were used to search for the relevant published English language studies and case reports relating to endocrine abnormalities and tuberculosis in Africa up to July 2013. The search terms used were endocrine dysfunction, endocrine abnormalities, adrenal insufficiency, diabetes mellitus, thyroid dysfunction, hypogonadism, disorders of calcium and vitamin D metabolism, tuberculosis, Africa. Reference lists of the identified articles were further used to identify other studies. Adrenal insufficiency, diabetes mellitus and calcium-vitamin D abnormalities were the most prevalent and frequently reported endocrine disorders among adult patients with tuberculosis in Africa. A meticulous endocrine evaluation among tuberculosis patients with suspected endocrine abnormalities should be encouraged in Africa and other high TB endemic regions. Treatment of these endocrine disorders has generally been shown to improve quality of life and reduce mortality.


How to cite this article:
Kibirige D. Endocrine dysfunction among adult patients with tuberculosis: An African experience.Indian J Endocr Metab 2014;18:288-294


How to cite this URL:
Kibirige D. Endocrine dysfunction among adult patients with tuberculosis: An African experience. Indian J Endocr Metab [serial online] 2014 [cited 2019 Aug 25 ];18:288-294
Available from: http://www.ijem.in/article.asp?issn=2230-8210;year=2014;volume=18;issue=3;spage=288;epage=294;aulast=Kibirige;type=0