Indian Journal of Endocrinology and Metabolism

ORIGINAL ARTICLE
Year
: 2014  |  Volume : 18  |  Issue : 3  |  Page : 407--409

Diabetic retinopathy in acromegaly


Said Azzoug, Farida Chentli 
 Department of Endocrine and Metabolic Diseases, Bab El Oued Hospital, 5boulevard Said Touati, Algiers, 16000, Algeria

Correspondence Address:
Farida Chentli
Department of Endocrine and Metabolic Diseases, Bab El Oued Hospital, 5boulevard Said Touati, Algiers - 16000
Algeria

Introduction: Although growth hormone (GH) has been implicated in the pathogenesis of diabetic retinopathy (DR), DR is deemed to be rare in patients with GH excess. Our aim was to study its prevalence in subjects with acromegaly suffering from diabetes mellitus (DM), to analyze its characteristics, and to look for predictive factors such as age at diagnosis, GH concentration and duration, DM duration, DM control, and family background. Materials and Methods: Forty patients with acromegaly and DM (21 males, 19 females), median age = 50 years, underwent a systematic ophthalmological examination with dilated funduscopy to seek diabetic retinopathy. Results: Among this population, 05 (12.5%) had DR. It was at an early stage or background retinopathy in 3 cases and at a more advanced stage or proliferative retinopathy in 2 cases. We did not find any correlation with age at diagnosis, GH levels and duration, DM duration and family history of DM, but poor glycemic control seems to play a role although statistical analysis showed borderline significance. Conclusion: From this study, we conclude that prevalence of DR in patients with acromegaly is 12.5%, and it is slight or moderate. Among studied factors, only poor glycemic control seems to be implicated in its development.


How to cite this article:
Azzoug S, Chentli F. Diabetic retinopathy in acromegaly.Indian J Endocr Metab 2014;18:407-409


How to cite this URL:
Azzoug S, Chentli F. Diabetic retinopathy in acromegaly. Indian J Endocr Metab [serial online] 2014 [cited 2019 Aug 24 ];18:407-409
Available from: http://www.ijem.in/article.asp?issn=2230-8210;year=2014;volume=18;issue=3;spage=407;epage=409;aulast=Azzoug;type=0