Indian Journal of Endocrinology and Metabolism

BRIEF COMMUNICATION
Year
: 2018  |  Volume : 22  |  Issue : 6  |  Page : 848--851

Flash glucose monitoring in subjects with diabetes on hemodialysis: A pilot study


Rajesh S Javherani1, Vedavati B Purandare2, Anjali A Bhatt2, Suganthi S Kumaran2, Mehmood G Sayyad3, Ambika G Unnikrishnan2 
1 Department of Clinical Nephrology and Critical Care, Chellaram Diabetes Institute, Pune, Maharashtra, India
2 Department of Clinical Diabetology and Endocrinology, Chellaram Diabetes Institute, Pune, Maharashtra, India
3 Department of Biostatistics, Chellaram Diabetes Institute, Pune, Maharashtra, India

Correspondence Address:
Ambika G Unnikrishnan
Chellaram Diabetes Institute, Bavdhan Budruk, Pune, Maharashtra - 411 021
India

Background: In patients with diabetes related end-stage renal disease (ESRD) on hemodialysis, blood glucose management can be challenging due to the kinetics of glucose and insulin in addition to other factors. The glucose monitoring systems which measure glucose levels continuously may be useful to study the glucose profile of patients with diabetes undergoing hemodialysis. Our study is designed to use ambulatory glucose profile to study the glucose pattern – during, before, and after a session of hemodialysis. Materials and Methods: Ten patients with type 2 diabetes with ESRD undergoing hemodialysis were recruited. Forty-eight glucose readings were recorded in a 12-h period which included 4 h each prior, during, and after the dialysis session with a flash glucose monitor (FreeStyle Libre-pro). The same 12 h time frame was also monitored on a non-dialysis day. Results: On the day of dialysis, the mean glucose level was significantly lower (P = 0.013) compared to the day without dialysis (95 ± 12.7 mg/dl vs 194 ± 76.8 mg/dl). As compared to the pre-dialysis period, the mean blood glucose levels during dialysis were lower (P = 0.004). As compared to the dialysis period, the mean blood glucose levels in the post-dialysis period were higher but did not reach statistical significance. Conclusion: In our study, subjects with type 2 diabetes on hemodialysis had lower glucose levels on the day of dialysis compared to non-dialysis day. Glucose levels showed a fall during hemodialysis and then a rise to higher levels after dialysis.


How to cite this article:
Javherani RS, Purandare VB, Bhatt AA, Kumaran SS, Sayyad MG, Unnikrishnan AG. Flash glucose monitoring in subjects with diabetes on hemodialysis: A pilot study.Indian J Endocr Metab 2018;22:848-851


How to cite this URL:
Javherani RS, Purandare VB, Bhatt AA, Kumaran SS, Sayyad MG, Unnikrishnan AG. Flash glucose monitoring in subjects with diabetes on hemodialysis: A pilot study. Indian J Endocr Metab [serial online] 2018 [cited 2019 Aug 26 ];22:848-851
Available from: http://www.ijem.in/article.asp?issn=2230-8210;year=2018;volume=22;issue=6;spage=848;epage=851;aulast=Javherani;type=0