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  Indian J Med Microbiol
 

Figure 4: Secondary end points: Mean/median percent change from baseline in BMD in total hip, femoral neck, and trochanter and bone turnover markers (ITTE population) * Error bars are 95% confidence intervals (CIs) from the model % change = treatment + baseline BMD. Denosumab group: n = 87; placebo group: n = 86 † Mean treatment difference (95% CI) and P-value at six months based on ANCOVA. ‡ Error bars are (Q1, Q3). At Month 6, denosumab group: n = 105; placebo group: n = 113. § Median treatment difference (95% CI) and P-value at six months based on Hodges-Lehmann Estimate and Wilcoxon rank-sum test. ǀǀError bars are (Q1, Q3). At Month 6, denosumab group: n = 104; placebo group: n = 113. ANCOVA = Analysis of covariance; BMD: bone mineral density; ITTE: intent-to-treat efficacy; s-CTX: serum C-terminal telopeptide of type I collagen; s-PINP: serum procollagen type I N propeptide

Figure 4: Secondary end points: Mean/median percent change from baseline in BMD in total hip, femoral neck, and trochanter and bone turnover markers (ITTE population) * Error bars are 95% confidence intervals (CIs) from the model % change = treatment + baseline BMD. Denosumab group: <i>n</i> = 87; placebo group: <i>n</i> = 86 † Mean treatment difference (95% CI) and <i>P</i>-value at six months based on ANCOVA. ‡ Error bars are (Q1, Q3). At Month 6, denosumab group: <i>n</i> = 105; placebo group: <i>n</i> = 113. § Median treatment difference (95% CI) and <i>P</i>-value at six months based on Hodges-Lehmann Estimate and Wilcoxon rank-sum test. ǀǀError bars are (Q1, Q3). At Month 6, denosumab group: <i>n</i> = 104; placebo group: <i>n</i> = 113. ANCOVA = Analysis of covariance; BMD: bone mineral density; ITTE: intent-to-treat efficacy; s-CTX: serum C-terminal telopeptide of type I collagen; s-PINP: serum procollagen type I N propeptide