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Year : 1997  |  Volume : 1  |  Issue : 1  |  Page : 22-26

Management Of Male Infertility -- An Assay Used To Assess Sperm Membrane Integrity

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S. P Dandekar

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Functional and morphological integrity of the sperm membrane was assessed by the ‘water test’, using distilled water as a hypoosmotic medium. Among 35 men with idiopathic infertility and 15 fertile men, good correlation between (b-g) type swollen sperm was observed for sperm concentration (r=0.63, p<0.001) and percent motility (r=0.53, p< 0.001). The percentage of swollen sperm was significantly different between fertile and infertile men. Thus ‘water test’ is simple and reliable to evaluate sperm membrane integrity.

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