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We present the clinical and possible etiological factors in twelve children who presented with precocious sexual development over an eight year period at out Center. There were nine girls and three boys. Eight had true isosexual precocious puberty. Two had primary hypothyroidism; of the other six (four girls and two boys), one boy had suprasellar mass. The mean age of six children with true isosexual precocious puberty was six years. Two girls had congenital adrenal hyperplasia. Two other girls had premature thelarche.