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Year : 2006  |  Volume : 8  |  Issue : 1  |  Page : 31-33

Utility Of 99m Tc Sestamibi In Mc Cune Albright Syndrome - A Report Of Two Cases



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U Rajnikanth


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McCune-Albright syndrome is characterized by fibrous dysplasia, café-au-lait pigmentation and multiple endocrine hyperfunction, most commonly precocious puberty in girls. Not all features of the syndrome may be present at initial diagnosis. We report two cases of precocious puberty, where McCune-Albright syndrome was diagnosed by the help of 99mTc-MDP (methylendiphosphonate) bone scan. The diagnosis of McCune-Albright syndrome is particularly useful where difficulties are encountered in etiological workup of gonadotropin independent precocious puberty in girls. In this setting, the diagnosis of McCune-Albright Syndrome could help in differentiation from an autonomous ovarian cyst or neoplasm, and prevent unnecessary surgery in these patients. We suggest that a bone scan is very useful in the evaluation of female subjects with gonadotropin independent precocious puberty.


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