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Year : 2008  |  Volume : 12  |  Issue : 4  |  Page : 35-37

Allgrove’s Syndrome Presenting As An Acute Adrenal Insufficiency Common Presentation Of An Uncommon Disorder



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Bhat Mohammad Hayat


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Allgrove syndrome is a rare autosomal recessive disorder characterized by the triad of alacrima, achalasia and adrenal insufficiency due to ACTH resistance (the triple A Syndrome). The syndrome usually presents during the first decade of life with dysphagia or severe (occasionally fatal) hypoglycaemic or hypotensive attack, related to adrenal insufficiency. A twenty five year old male developed worsening skin pigmentation. Patient had previously been operated for achlasia cardia at the age of six years. Investigations revealed, patient had acute adrenal insufficiency and alacrima and a diagnosis of Allgrove’s syndrome was made.


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