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Year : 2011  |  Volume : 15  |  Issue : 2  |  Page : 140-142

Acromegaly associated with a symptomatic Rathke's cyst

1 Department of Endocrinology, Jaslok Hospital and Research Centre, Mumbai, India
2 Department of Medicine and Endocrinology, Bart and The London NHS Trust, London, United Kingdom
3 Department of Medicine and Endocrinology, Jaslok Hospital and Research Centre, Mumbai, India
4 Department of Histopathology, Saifee Hospital, Mumbai, India

Correspondence Address:
Vishal Gupta
Jaslok Hospital and Research Centre, 15 - Dr. Deshmukh Marg, Pedder Road, Mumbai - 400 026
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/2230-8210.81950

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Our aim is to describe a case of acromegaly that was associated with symptomatic Rathke's cyst. We describe a young male student without any significant family history who presented with clinical and biochemical features consistent with growth hormone excess, which was confirmed with dynamic testing. He also described a persistent headache predating symptoms of growth hormone excess by 4 years. Magnetic resonance imaging (MRI) of the pituitary showed a large sellar mass which was thought to be a somatotroph adenoma. Trans-sphenoidal surgery was performed; however, a colloid lesion was identified by the neurosurgeon that proved to be a Rathke's cyst. The association of acromegaly with Rathke's cyst is very rare, with less than 10 cases found to be reported on review of literature. This is the first report from India.

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