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Year : 2012  |  Volume : 16  |  Issue : 2  |  Page : 297-299

Gitelman's syndrome with panhypopituitarism: Reno-endocrine interplay

1 Department of Endocrinology, Command Hospital (Air Force), Bangalore, India
2 Department of Medicine, Command Hospital (Air Force), Bangalore, India
3 Department of Neurology, Command Hospital (Air Force), Bangalore, India
4 Department of Nephrology, Command Hospital (Air Force), Bangalore, India

Correspondence Address:
Vimal Upreti
Department of Endocrinology, Command Hospital (Air Force), Bangalore - 560 007
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/2230-8210.93774

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Gitelman's syndrome is an inherited tubulopathy affecting thiazide-sensitive sodium chloride cotransporter, which manifests with hypokalemic alkalosis, hypomagnesemia, and hypocalciuria. Recently few cases have been described having an association of Gitelman's syndrome with pituitary abnormalities on imaging, though with normal hormonal status. We describe the first case of an adult patient having Gitelman's syndrome and hypopituitarism with abnormal pituitary imaging. She presented to us with hypotension, hypokalemia, hypomagnesemia with alkalosis, hypothyroidism, hypocortisolism, and hypogonadism. She was treated with replacement of electrolytes and hormones, to which she showed an excellent response.

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