| ORIGINAL ARTICLE |
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| Year : 2012 | Volume
: 16
| Issue : 3 | Page : 414-416 |
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Pulmonary function tests in patients with primary hyperparathyroidism
Sanjay Kumar Bhadada1, Ahutosh Agrawal2, Viral N Shah1, Anil Bhansali1, Arnanshu Behera3, Anish Bhattacharya4, Uma Nahar5
1 Department of Endocrinology, Postgraduate Institute of Medical Education and Research, Chandigarh (UT), India
2 Department of Pulmonary Medicine, Postgraduate Institute of Medical Education and Research, Chandigarh (UT), India
3 Department of Surgery, Postgraduate Institute of Medical Education and Research, Chandigarh (UT), India
4 Department of Gastroenterology, Postgraduate Institute of Medical Education and Research, Chandigarh (UT), India
5 Department of Pathology, Postgraduate Institute of Medical Education and Research, Chandigarh (UT), India
Correspondence Address:
Sanjay Kumar Bhadada
Department of Endocrinology, Postgraduate Institute of Medical Education and Research, Chandigarh (UT)
India
 Source of Support: None, Conflict of Interest: None  | Check |
DOI: 10.4103/2230-8210.95685
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Context: There is limited information on respiratory muscle functions in patients with primary hyperparathyroidism (PHPT). AIM: To assess respiratory muscle dysfunction in patients with PHPT. Setting and Design: This prospective study was carried between January 2005 and December 2006 by the Department of Endocrinology at the Postgraduate Institute of Medical Education and Research, Chandigarh. Materials and Methods: PHPT was defined as elevated parathyroid hormone in the presence of hypercalcemia. Spirometry was performed using a dry rolling seal spirometer and spirometric indices like forced vital capacity (FVC), forced expiratory volume in first second (FEV 1 ), and FEV 1 /FVC ratio were measured using standard guidelines. Results: Thirty patients were studied with a mean age of 37.1 ± 2.4 years and 18 were women. The most common presenting symptoms were fatigue (75.0%) and bone pain (60.70%). The mean (±SD) of percentage predicted FVE 1 , FVC, FEV 1 /FVC ratio, PEF, and FEF were 98.7 ± 16.1, 93.9 ± 14.7, 84.5 ± 3.4, 89.3 ± 22.5, and 99.7 ± 33.6, respectively. Two had obstructive lung disease and two had restrictive lung disease. We did not find correlation with preoperative serum calcium, phosphate, and PTH with FVE 1 , FVC, FEV 1 /FVC ratio, PEF, and FEF. Conclusion: Elevated calcium, low phosphate, and elevated PTH levels in patients with moderate to severe PHPT do not significantly affect respiratory muscle functions. |
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