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Year : 2013  |  Volume : 17  |  Issue : 1  |  Page : 76-82

Vitamin D in pregnancy: A metabolic outlook

1 Department of Obsteterics and Gynaecology, MGM Medical College, Indore, Madhya Pradesh, India
2 Department of Obstetrics and Gynaecology, Obstetrician, Gynaecologist and Endoscopic Surgeon, Air Force Hospital, Kanpur, Uttar Pradesh, India

Correspondence Address:
Manila Kaushal
403, Utsav Avenue, 12/5 Usha ganj, Jaora Compound, Indore - 452 001, Madhya Pradesh
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/2230-8210.107862

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Vitamin D deficiency is a preventable health problem. Vitamin D deficiency among pregnant women is frequent in many populations over the world. Research indicates that adequate vitamin D intake in pregnancy is optimal for maternal, fetal and child health. Adverse health outcomes during pregnancy are preeclampsia; gestational diabetes mellitus and caesarean section. Consequences in newborns are low birth weight, neonatal rickets, a risk of neonatal hypocalcaemia, asthma and/or type 1 diabetes. Vitamin D deficiency during pregnancy is the origin for a host of future perils for the child, especially effect on neurodevelopment and immune system. Some of this damage done by maternal Vitamin D deficiency gets evident after many years. Therefore, prevention of vitamin D deficiency among pregnant women is essential. The currently recommended supplementation amount of vitamin D is not sufficient to maintain a value of 25 hydroxy vitamin D above 30 ng/ml, during pregnancy. Studies are underway to establish the recommended daily doses of vitamin D in pregnant women. Clearly, further investigation is required into the effects of vitamin D, of vitamin D supplementation, and of vitamin D analogs for improvement in human health generally and mothers and children specifically. This review discusses vitamin D metabolism, dietary requirements and recommendations and implications of vitamin D deficiency during pregnancy and lactation.

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