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Year : 2018  |  Volume : 22  |  Issue : 5  |  Page : 705-709

PHPT masquerading as rickets in children and presenting with rare skeletal manifestations: Report of three cases and review of literature

1 Department of Endocrine Surgery, Dr RMLIMS, Lucknow, Uttar Pradesh, India
2 Department of Endocrinology, SGPGIMS, Lucknow, Uttar Pradesh, India

Correspondence Address:
Amit Agarwal
Department of Endocrine Surgery, Sanjay Gandhi Post Graduate Institute of Medical Sciences (SGPGIMS), Lucknow - 226 014, Uttar Pradesh
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/ijem.IJEM_54_18

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Primary hyperparathyroidism (PHPT) is an uncommon condition in children and adolescents. However, rapid growth spurt during puberty may result in unmasking and development of certain skeletal manifestations of PHPT. We present three cases of PHPT associated with rare skeletal manifestations of rickets. All three patients had radiological evidence of rickets with primary hyperparathyroidism. All the three patients had single gland adenoma. Literature is sparse regarding reversal of features of rickets following parathyroidectomy. In all three patients of our series, there was a complete resolution of bone/joint pain. However, in two children only the genu valgum persisted but their growth was normal and they had no proximal muscle weakness. In another child multiple corrective surgeries were done to correct the deformities.

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