Indian Journal of Endocrinology and Metabolism

REVIEW ARTICLE
Year
: 2012  |  Volume : 16  |  Issue : 3  |  Page : 339--342

Bisphenol A in dental sealants and its estrogen like effect


Manu Rathee1, Poonam Malik2, Jyotirmay Singh3 
1 Department of Prosthodontics, Post Graduate Institute of Dental Sciences (PGIDS), Pt. B.D. Sharma University of Health Sciences, Rohtak, India
2 Department of Prosthodontics, SGT Dental College, Hospital and Research Institute, Gurgaon, Haryana, India
3 Department of Orthodontics and Dentofacial Orthopedics, Dr. B.R. Ambedkar Institute of Dental Sciences and Research, Patna, Bihar, India

Correspondence Address:
Manu Rathee
Senior Professor & Head of Department, Prosthodontics, Post Graduate Institute of Dental Sciences (PGIDS), Pt. B. D. Sharma University of Health Sciences, Rohtak, Haryana-124001
India

Bisphenol A or BPA-based epoxy resins are widely used in the manufacture of commercial products, including dental resins, polycarbonate plastics, and the inner coating of food cans. BPA is a precursor to the resin monomer Bis-GMA. During the manufacturing process of Bis-GMA dental sealants, Bisphenol A (BPA) might be present as an impurity or as a degradation product of Bis-DMA through esterases present in saliva. Leaching of these monomers from resins can occur during the initial setting period and in conjunction with fluid sorption and desorption over time and this chemical leach from dental sealants may be bioactive. Researchers found an estrogenic effect with BPA, Bis-DMA, and Bis-GMA because BPA lacks structural specificity as a natural ligand to the estrogen receptor. It generated considerable concern regarding the safety of dental resin materials. This review focuses on the BPA in dental sealants and its estrogen-like effect.


How to cite this article:
Rathee M, Malik P, Singh J. Bisphenol A in dental sealants and its estrogen like effect.Indian J Endocr Metab 2012;16:339-342


How to cite this URL:
Rathee M, Malik P, Singh J. Bisphenol A in dental sealants and its estrogen like effect. Indian J Endocr Metab [serial online] 2012 [cited 2021 Apr 13 ];16:339-342
Available from: https://www.ijem.in/article.asp?issn=2230-8210;year=2012;volume=16;issue=3;spage=339;epage=342;aulast=Rathee;type=0