Indian Journal of Endocrinology and Metabolism

: 2012  |  Volume : 16  |  Issue : 3  |  Page : 447--449

Ogilvie俟Q製 syndrome in a case of myxedema coma

Uday Yanamandra1, Narendra Kotwal2, Anil Menon1, Velu Nair1 
1 Department of Internal Medicine, Armed Forces Medical College, Pune, India
2 Department of Endocrinology, Command Hospital, Pune, Maharashtra, India

Correspondence Address:
Narendra Kotwal
Department of Endocrinology, Command Hospital (Southern Command), Pune - 411 040, Maharashtra

Ogilvie俟Q製 syndrome [acute colonic pseudo-obstruction (ACPO)] presents as massive colonic dilatation without a mechanical cause, usually in critically ill patients due to imbalanced sympathetic and parasympathetic activity. The initial therapy remains conservative with supportive measures (correction of metabolic, infectious or pharmacologic factors) followed by neostigmine and decompressive colonoscopy. Surgery is reserved for patients with clinical deterioration or with evidence of colonic ischemia or perforation. A 60-year-old lady presented with fever, altered sensorium, obstipation, bradycardia and abdominal distension. Investigation revealed hyponatremia and acute colonic pseudo-obstruction. Supportive measures and decompressive colonoscopy were not of great benefit. Thyroid profile was suggestive of primary hypothyroidism. Colonic motility was restored only on starting thyroxin. The case is illustrative of the need to consider hypothyroidism, a common endocrine disorder, in the differential diagnosis of Ogilvie俟Q製.

How to cite this article:
Yanamandra U, Kotwal N, Menon A, Nair V. Ogilvie's syndrome in a case of myxedema coma.Indian J Endocr Metab 2012;16:447-449

How to cite this URL:
Yanamandra U, Kotwal N, Menon A, Nair V. Ogilvie's syndrome in a case of myxedema coma. Indian J Endocr Metab [serial online] 2012 [cited 2021 Apr 14 ];16:447-449
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