Indian Journal of Endocrinology and Metabolism

ORIGINAL ARTICLE
Year
: 2013  |  Volume : 17  |  Issue : 8  |  Page : 542--546

Clinical experience with insulin detemir, biphasic insulin aspart and insulin aspart in people with type 2 diabetes: Results from the Andhra Pradesh cohort of the A 1 chieve study


Mohammed Abubaker1, Y Sadasiva Rao2, Samir Hamid Zargar3, Raman Shetty3, Ravi Shankar4 
1 Deccan College of Medical Sciences, Hyderabad, Andhra Pradesh, India
2 Yalamanchi Diabetes Specialties Centre, Vijayawada, Andhra Pradesh, India
3 Novo Nordisk India Pvt. Ltd., Bangalore, India
4 Apollo Health City, Hyderabad, Andhra Pradesh, India

Correspondence Address:
Raman Shetty
Novo Nordisk India Pvt. Ltd., Plot No.32, 47 - 50, EPIP Area, Whitefield, Bangalore
India

Background: The A 1 chieve, a multicentric (28 countries), 24-week, non-interventional study evaluated the safety and effectiveness of insulin detemir, biphasic insulin aspart and insulin aspart in people with T2DM (n = 66,726) in routine clinical care across four continents. Materials and Methods: Data was collected at baseline, at 12 weeks and at 24 weeks. This short communication presents the results for patients enrolled from Andhra Pradesh, India. Results: A total of 3077 patients were enrolled in the study. Four different insulin analogue regimens were used in the study. Patients had started on or were switched to biphasic insulin aspart (n = 2452), insulin detemir (n = 308), insulin aspart (n = 226), basal insulin plus insulin aspart (n = 21) and other insulin combinations (n = 68). At baseline glycaemic control was poor for both insulin naïve (mean HbA 1 c: 8.9%) and insulin user (mean HbA 1 c: 9.2%) groups. After 24 weeks of treatment, both the groups showed improvement in HbA 1 c (insulin naïve: −1.2%, insulin users: −1.1%). SADRs including major hypoglycaemic events or episodes did not occur in any of the study patients. Conclusion: Starting or switching to insulin analogues was associated with improvement in glycaemic control with a low rate of hypoglycaemia.


How to cite this article:
Abubaker M, Rao Y S, Zargar SH, Shetty R, Shankar R. Clinical experience with insulin detemir, biphasic insulin aspart and insulin aspart in people with type 2 diabetes: Results from the Andhra Pradesh cohort of the A 1 chieve study.Indian J Endocr Metab 2013;17:542-546


How to cite this URL:
Abubaker M, Rao Y S, Zargar SH, Shetty R, Shankar R. Clinical experience with insulin detemir, biphasic insulin aspart and insulin aspart in people with type 2 diabetes: Results from the Andhra Pradesh cohort of the A 1 chieve study. Indian J Endocr Metab [serial online] 2013 [cited 2020 Oct 22 ];17:542-546
Available from: https://www.ijem.in/article.asp?issn=2230-8210;year=2013;volume=17;issue=8;spage=542;epage=546;aulast=Abubaker;type=0