Indian Journal of Endocrinology and Metabolism

ORIGINAL ARTICLE
Year
: 2017  |  Volume : 21  |  Issue : 3  |  Page : 434--438

Pubertal onset in apparently healthy Indian boys and impact of obesity


Vineet Surana1, Aashima Dabas1, Rajesh Khadgawat1, Raman Kumar Marwaha2, V Sreenivas3, M Ashraf Ganie1, Nandita Gupta1, Neena Mehan4 
1 Department of Endocrinology and Metabolism, All India Institute of Medical Sciences, New Delhi, India
2 International Life Sciences Institute, New Delhi, India
3 Department of Biostatistics, All India Institute of Medical Sciences, New Delhi, India
4 Sur Homeopathic Medical College, Hospital and Research Centre, New Delhi, India

Correspondence Address:
Raman Kumar Marwaha
Flat No. 17, Gautam Apartments, Gautam Nagar, New Delhi - 110 049
India

Objective: Primary - to determine the age of pubertal onset in Indian boys. Secondary - (a) to assess the impact of obesity on pubertal timing, (b) to assess the relationship between gonadotropins and puberty. Design: Cross-sectional. Setting: General community-seven schools across New Delhi. Participants: Random sample of 1306 school boys, aged 6–17 years. Materials and Methods: Anthropometric measurement for weight and height and pubertal staging was performed for all subjects. Body mass index (BMI) was calculated to define overweight/obesity. Serum luteinizing hormone (LH), follicle stimulating hormone, and serum testosterone were measured in every sixth subject. Main Outcome Measure: Age at pubertal onset-testicular volume ≥4 mL (gonadarche) and pubic hair Stage II. Results: Median age of attaining gonadarche and pubarche was 10.41 years (95% confidence interval [CI]: 10.2–10.6 years) and 13.60 (95% CI: 13.3–14.0 years), respectively. No significant difference in the age of attainment of gonadarche was observed in boys with normal or raised BMI, though pubarche occurred 8 months earlier in the latter group. Serum gonadotropins and testosterone increased with increasing stages of puberty but were unaffected by BMI. Serum LH level of 1.02 mIU/mL and testosterone level of >0.14 ng/mL showed the best prediction for pubertal onset. Conclusion: The study establishes a secular trend of the age of onset of puberty in Indian boys. Pubarche occurred earlier in overweight/obese boys. The cutoff levels of serum LH and testosterone for prediction of pubertal onset have been established.


How to cite this article:
Surana V, Dabas A, Khadgawat R, Marwaha RK, Sreenivas V, Ganie M A, Gupta N, Mehan N. Pubertal onset in apparently healthy Indian boys and impact of obesity.Indian J Endocr Metab 2017;21:434-438


How to cite this URL:
Surana V, Dabas A, Khadgawat R, Marwaha RK, Sreenivas V, Ganie M A, Gupta N, Mehan N. Pubertal onset in apparently healthy Indian boys and impact of obesity. Indian J Endocr Metab [serial online] 2017 [cited 2021 Sep 25 ];21:434-438
Available from: https://www.ijem.in/article.asp?issn=2230-8210;year=2017;volume=21;issue=3;spage=434;epage=438;aulast=Surana;type=0