Indian Journal of Endocrinology and Metabolism

BRIEF COMMUNICATION
Year
: 2017  |  Volume : 21  |  Issue : 5  |  Page : 776--780

Effect of a low-calorie diet on restoration of normoglycemia in obese subjects with type 2 diabetes


Anjali Amit Bhatt1, Priya K Choudhari2, Rutuja R Mahajan2, Mehmood G Sayyad3, Devi D Pratyush4, Imtiaz Hasan5, Rajesh S Javherani1, Manish M Bothale1, Vedavati B Purandare1, Ambika Gopalakrishnan Unnikrishnan1 
1 Department of Clinical Diabetology and Endocrinology, Chellaram Diabetes Institute, Pune, Maharashtra, India
2 Department of Dietetics and Nutrition, Chellaram Diabetes Institute, Pune, Maharashtra, India
3 Department of Biostatistics, Chellaram Diabetes Institute, Pune, Maharashtra, India
4 Department of Research, Chellaram Diabetes Institute, Pune, Maharashtra, India
5 Department of Pathology, Chellaram Diabetes Institute, Pune, Maharashtra, India

Correspondence Address:
Ambika Gopalakrishnan Unnikrishnan
Department of Clinical Diabetology and Endocrinology, Chellaram Diabetes Institute, Lalani Quantum, Pune-Bangalore Highway, Pune, Maharashtra
India

Introduction: Type 2 diabetes mellitus (T2DM) is considered to be an inevitably progressive disease. Complex therapies add to the financial and psychological burden. Very low-calorie diets (LCDs) are emerging as an option in the management of type 2 diabetes. Methods: We performed a clinical audit of patients with T2DM who received 12 weeks of LCD. Results: This case series documents that 6 out of 12 participants (median baseline HbA1c 9%) achieved HbA1c level in nondiabetes range with LCD despite stopping all antidiabetes medications. There was an improvement in serum triglycerides, HDL cholesterol, total cholesterol, C-Reactive protein, urine microalbumin, liver transaminases, liver fat and the indices of insulin resistance, beta cell secretory capacity, and insulin sensitivity. Conclusion: If long-term follow-up proves sustained benefits, such dietary restriction may be an alternative to more drastic options for reversal of type 2 diabetes. This may also help in changing the treatment perspective of a newly detected T2DM from an incurable and inevitably progressive disease to a potentially reversible disease.


How to cite this article:
Bhatt AA, Choudhari PK, Mahajan RR, Sayyad MG, Pratyush DD, Hasan I, Javherani RS, Bothale MM, Purandare VB, Unnikrishnan AG. Effect of a low-calorie diet on restoration of normoglycemia in obese subjects with type 2 diabetes.Indian J Endocr Metab 2017;21:776-780


How to cite this URL:
Bhatt AA, Choudhari PK, Mahajan RR, Sayyad MG, Pratyush DD, Hasan I, Javherani RS, Bothale MM, Purandare VB, Unnikrishnan AG. Effect of a low-calorie diet on restoration of normoglycemia in obese subjects with type 2 diabetes. Indian J Endocr Metab [serial online] 2017 [cited 2021 Jun 23 ];21:776-780
Available from: https://www.ijem.in/article.asp?issn=2230-8210;year=2017;volume=21;issue=5;spage=776;epage=780;aulast=Bhatt;type=0