Indian Journal of Endocrinology and Metabolism

REVIEW ARTICLE
Year
: 2017  |  Volume : 21  |  Issue : 6  |  Page : 903--908

Osteogenesis imperfecta


Justin Easow Sam, Mala Dharmalingam 
 Department of Endocrinology, Ramaiah Medical College, Bengaluru, Karnataka, India

Correspondence Address:
Mala Dharmalingam
Department of Endocrinology, Ramaiah Medical College, MSRIT Post, Bengaluru - 560 054, Karnataka
India

Osteogenesis imperfecta is a common heritable connective tissue disorder. Nearly ninety percent are due to Type I collagen mutations. Type I-IV are autosomal dominant, and Type VI–XIII are autosomal recessive. They are Graded 1-5 based on severity. Genomic testing is done by collagen analysis from fibroblasts. The mainstay of treatment is bisphosphonate therapy. The prognosis is variable.


How to cite this article:
Sam JE, Dharmalingam M. Osteogenesis imperfecta.Indian J Endocr Metab 2017;21:903-908


How to cite this URL:
Sam JE, Dharmalingam M. Osteogenesis imperfecta. Indian J Endocr Metab [serial online] 2017 [cited 2021 Sep 28 ];21:903-908
Available from: https://www.ijem.in/article.asp?issn=2230-8210;year=2017;volume=21;issue=6;spage=903;epage=908;aulast=Sam;type=0