Indian Journal of Endocrinology and Metabolism

ORIGINAL ARTICLE
Year
: 2018  |  Volume : 22  |  Issue : 1  |  Page : 89--92

Lipid profile in relation to glycemic control in Type 1 diabetes children and adolescents in Bangladesh


Bedowra Zabeen1, Ana Margarida Balsa2, Nasreen Islam1, Mukta Parveen3, Jebun Nahar1, Kishwar Azad1 
1 Department of Paediatrics and CDiC BIRDEM, Dhaka, Bangladesh
2 Department of Paediatrics and CDiC BIRDEM, Dhaka, Bangladesh; Diabetes E Nutrição Do Centro Hospitalar Do Baixo Vouga, Aveiro, Portugal
3 Department of Biochemistry, Gazi Medical College, Khulna, Bangladesh

Correspondence Address:
Bedowra Zabeen
Department of Paediatrics and CDiC BIRDEM 2 1/A Shegunbagicha, Dhaka 1000
Bangladesh

Introduction: Dyslipidemia and hyperglycemia are metabolic abnormalities commonly found in young patients with Type 1 diabetes mellitus (T1DM) and both increase the risk of cardiovascular disease. Methods: This cross-sectional study was aimed to evaluate the pattern of dyslipidemia and its relationship with other risk factors in children and adolescents with T1DM. A total of 576 T1DM patients aged 10–18 years who attended Changing Diabetes in Children, a pediatric diabetes clinic in Bangladesh Institute of Research and Rehabilitation for Diabetes, Endocrine and Metabolic Disorders over 1 year period from July 2015 to June 2016 were included in this study.Results: The overall frequency of dyslipidemia was 65%. The high triglyceride, high cholesterol, high low-density lipoprotein (LDL) and low high-density lipoprotein were found in 50%, 66%, 75%, and 48%, respectively. Compared to patients without dyslipidemia, patients with dyslipidemia had significantly lower mean body mass index (kg/m2) (18.4 [interquartile range; 16.2–21.4] vs. 19.5 [17.3–21.5] (P = 0.005)); significantly higher median fasting blood sugar (12.7 [9.9–15.2] vs. 10.6 [7.9–12.6] (P < 0.0001)) and higher median glycosylated hemoglobin (9.8 [8.4–11.8] vs. 7.9 [9.3–10.5] (P < 0.0001)). Hypertension was significantly higher in dyslipidemic patients (9.4% vs. 2.5% P < 0.002). Conclusion: More than half (65%) of our children and adolescents with T1DM had dyslipidemia, among them high LDL was the most common. These findings emphasize the screening of lipid profile in T1DM children and adolescents.


How to cite this article:
Zabeen B, Balsa AM, Islam N, Parveen M, Nahar J, Azad K. Lipid profile in relation to glycemic control in Type 1 diabetes children and adolescents in Bangladesh.Indian J Endocr Metab 2018;22:89-92


How to cite this URL:
Zabeen B, Balsa AM, Islam N, Parveen M, Nahar J, Azad K. Lipid profile in relation to glycemic control in Type 1 diabetes children and adolescents in Bangladesh. Indian J Endocr Metab [serial online] 2018 [cited 2021 Sep 22 ];22:89-92
Available from: https://www.ijem.in/article.asp?issn=2230-8210;year=2018;volume=22;issue=1;spage=89;epage=92;aulast=Zabeen;type=0