Indian Journal of Endocrinology and Metabolism

ORIGINAL ARTICLE
Year
: 2018  |  Volume : 22  |  Issue : 1  |  Page : 93--99

Correlation of serum adiponectin and leptin levels in obesity and Type 2 diabetes mellitus


Arundhati G Diwan1, Aniket A Kuvalekar2, Siddharth Dharamsi1, Aditya M Vora1, Vivek A Nikam1, Abhijit A Ghadge2 
1 Department of Medicine, Bharati Vidyapeeth Medical College and Hospital, Bharati Vidyapeeth Deemed University, Pune, Maharashtra, India
2 Diabetes Laboratory, Interactive Research School for Health Affairs, Bharati Vidyapeeth Deemed University, Pune, Maharashtra, India

Correspondence Address:
Abhijit A Ghadge
Diabetes Laboratory, Interactive Research School for Health Affairs, Bharati Vidyapeeth Deemed University, Pune-Satara Road, Pune, Maharashtra
India

Introduction: Indian phenotype includes higher waist circumference despite lower body mass index, thereby making Indians more prone to diabetes and its complications. Aim: The present study aimed to analyze the serum levels of adiponectin and leptin in the participants with type 2 diabetes mellitus (T2DM) and obesity and their correlation with hypertension and dyslipidemia. Materials and Methods: In the study, 50 diabetics and 50 controls aged between 40 and 60 years were included in the study. Results: Adiponectin levels were significantly higher in diabetics than in nondiabetic participants irrespective of gender (P ≤ 0.04 in males, P ≤ 0.02 in females). Leptin levels were significantly higher in diabetics compared to nondiabetics (P ≤ 0.001) in both males and females. Conclusion: Adiponectin and leptin levels may be used as important clinical markers for T2DM and obesity.


How to cite this article:
Diwan AG, Kuvalekar AA, Dharamsi S, Vora AM, Nikam VA, Ghadge AA. Correlation of serum adiponectin and leptin levels in obesity and Type 2 diabetes mellitus.Indian J Endocr Metab 2018;22:93-99


How to cite this URL:
Diwan AG, Kuvalekar AA, Dharamsi S, Vora AM, Nikam VA, Ghadge AA. Correlation of serum adiponectin and leptin levels in obesity and Type 2 diabetes mellitus. Indian J Endocr Metab [serial online] 2018 [cited 2021 Sep 22 ];22:93-99
Available from: https://www.ijem.in/article.asp?issn=2230-8210;year=2018;volume=22;issue=1;spage=93;epage=99;aulast=Diwan;type=0