Indian Journal of Endocrinology and Metabolism

ORIGINAL ARTICLE
Year
: 2019  |  Volume : 23  |  Issue : 4  |  Page : 473--479

Assessment of anthropometric and physical health indicators before and after pituitary surgery in patients with nonfunctioning pituitary adenomas, acromegaly, and Cushing disease


Cyro G S. Leães1, Matheus V Fernandes2, Luiza Alves2, Bruna Araújo2, Carolina G. S L. Rech2, Nelson P Ferreira2, Luis H T. Rosa3, Júlia F S. Pereira-Lima4, Miriam C Oliveira4 
1 Programa de Pós-Graduação em Patologia, Universidade Federal de Ciências da Saúde de Porto Alegre (UFCSPA), Porto Alegre, RS, Brasil
2 Centro de Neuroendocrinologia, Complexo Hospitalar Santa Casa, UFCSPA, Porto Alegre, RS, Brasil
3 Programa de Pos-Graduacao em Ciencias da Reabilitacao, UFCSPA, Porto Alegre, RS, Brasil
4 Programa de Pós-Graduação em Patologia, Universidade Federal de Ciências da Saúde de Porto Alegre (UFCSPA); Centro de Neuroendocrinologia, Complexo Hospitalar Santa Casa, Porto Alegre, RS, Brasil

Correspondence Address:
Miriam C Oliveira
Rua Sarmento Leite, 245; Sala 402, Prédio 1/90050-170 - Porto Alegre, RS
Brasil

Introduction: Individuals with pituitary adenomas may have organic consequences of their disease or therapy, and psychological changes can compromise their quality of life (QoL). This study aimed to determine the anthropometric profile and health indicators of patients with pituitary adenoma before and after pituitary surgery. Methods: Forty-four patients were included in this study. Out of these, 22 patients had nonfunctioning adenomas (50%), 17 acromegaly (38.6%), and 5 patients with Cushing's disease (11.4%). Anthropometric measurements included body mass index (BMI), waist circumference (WC), and waist-to-hip ratio (WHR). Health indicators included body fat percentage (BF%), basal metabolic rate (BMR), maximal oxygen uptake (VO2max), and hand grip strength. Physical activity level (the International Physical Activity Questionnaire [IPAQ]), subjective perception of health, body image (Body Shape Questionnaire), body satisfaction (Stunkard Figure Rating Scale) were used. Results: The mean patient age was 47.2 ± 14.6 years; of which 25 were women (56.8%). Before surgery, 75.0% were overweight or obese, 84.1% had WC with risk of metabolic complications, and 90.0% had WHR with cardiovascular risk. There was a high BF% in 56.4% of cases, low BMR in 65.1%, lower VO2max in 16.2%, and below-average grip strength in 88.6%. Hypopituitary patients had poorer cardiorespiratory fitness. The IPAQ showed reduction in physical activity, and 79.5% of patients were dissatisfied with their body image. Patients with nonfunctioning adenomas had better perception of their health while those with Cushing's disease had more distorted body image. Postoperatively, patients with acromegaly showed improvement in WHR and physical activity level, and patients with Cushing's disease showed improvement in anthropometric variables. Conclusions: These findings emphasize the need for continuous monitoring of this population for anthropometric indicators associated with metabolic and cardiovascular comorbidities as well as body satisfaction.


How to cite this article:
S. Leães CG, Fernandes MV, Alves L, Araújo B, L. Rech CG, Ferreira NP, T. Rosa LH, S. Pereira-Lima JF, Oliveira MC. Assessment of anthropometric and physical health indicators before and after pituitary surgery in patients with nonfunctioning pituitary adenomas, acromegaly, and Cushing disease.Indian J Endocr Metab 2019;23:473-479


How to cite this URL:
S. Leães CG, Fernandes MV, Alves L, Araújo B, L. Rech CG, Ferreira NP, T. Rosa LH, S. Pereira-Lima JF, Oliveira MC. Assessment of anthropometric and physical health indicators before and after pituitary surgery in patients with nonfunctioning pituitary adenomas, acromegaly, and Cushing disease. Indian J Endocr Metab [serial online] 2019 [cited 2021 Apr 12 ];23:473-479
Available from: https://www.ijem.in/article.asp?issn=2230-8210;year=2019;volume=23;issue=4;spage=473;epage=479;aulast=S.;type=0