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  Indian J Med Microbiol
 

Figure 1: Pharmacodynamic and pharmacokinetic profiles for biphasic insulin aspart (BIAsp) 30, 50 and 70 and insulin aspart (IAsp). (a) Glucose infusion rate (GIR) profiles reflect the ratio of IAsp/protaminated IAsp in the formulations. (b) The early IAsp level increases and the late IAsp level decreases with a higher percentage of soluble aspart in the formulation. AUC, area under the curve; Cmax, maximum concentration Reprinted with permission from Heise T, Eckers U, Kanc K, Nielsen JN, Nosek L. The pharmacokinetic and pharmacodynamic properties of different formulations of biphasic insulin aspart: a randomized, glucose clamp, crossover study. Diabetes Technol Ther 2008;10:479-485. The publisher for this copyrighted material is Mary Ann Liebert, Inc. publishers

Figure 1: Pharmacodynamic and pharmacokinetic profiles for biphasic insulin aspart (BIAsp) 30, 50 and 70 and insulin aspart (IAsp). (a) Glucose infusion rate (GIR) profiles reflect the ratio of IAsp/protaminated IAsp in the formulations. (b) The early IAsp level increases and the late IAsp level decreases with a higher percentage of soluble aspart in the formulation. AUC, area under the curve; Cmax, maximum concentration Reprinted with permission from Heise T, Eckers U, Kanc K, Nielsen JN, Nosek L. The pharmacokinetic and pharmacodynamic properties of different formulations of biphasic insulin aspart: a randomized, glucose clamp, crossover study. Diabetes Technol Ther 2008;10:479-485. The publisher for this copyrighted material is Mary Ann Liebert, Inc. publishers